First of all, CONGRATULATIONS! Whether you have decided to try for a baby, you found out you’re pregnant, or you have already welcomed your bundle of joy and are looking to support your breastfeeding efforts, this is such an exciting time for you! And if you’re shopping for a loved one, you deserve congratulations as well!
Why are Prenatal Supplements Important?
Babies have a greater need for nutrients both during and after pregnancy. Mothers are also in greater need of prenatal nutrition to support their bodies in the exceptional process of growing a baby! It’s important to eat a healthy and balanced diet to support these needs, but a supplement designed for pregnant and lactating women helps ensure you get the much greater supply of nutrients you and your growing baby need. Smart Prenatal was specifically designed to support both mother and baby through this entire process. Of course, at BrainMD, we put added emphasis on the importance of brain health and development when formulating this prenatal supplement.
How is Smart Prenatal Different?
The ingredients in BrainMD's Smart Prenatal represent the most advanced research on the nutritional requirements of mother and baby during pregnancy and after birth. This high-purity formula is for mothers who want to ensure their nutrition supports baby’s fully functioning brain, eyes, and other organs, and good motor development. We also carefully selected the ingredients in this formula for their superior safety of long-term use, not only during the pregnancy period but postpartum as well, to promote adequate nutrient content of the breast milk during the lactation period.
Smart Prenatal includes all 8 B vitamins in their most active forms, including folate, as methylfolate which is better utilized by mother and baby than the synthetic folic acid. It also contains vitamins A, C, D, E and K2, as well as magnesium, calcium, lutein and zeaxanthin, potassium and more. A total of 28 crucial ingredients in dosages based on scientific research.
We made Smart Prenatal for smart mamas and smart babies!
Perfect for any mom or mom to be!
Ingredients & Facts
B Vitamins In Their Most Active Forms
The B vitamins are so fundamental to the baby's brain development that the brain has special transport systems to move these vitamins across the blood-brain barrier and deliver them to the brain cells. This formula supplies generous allowances of the best-utilized forms of all the B vitamins: B1, B2, B3, B5, B6, B12, folate and biotin. It is important for the mother to be well supplied with all the B vitamins during her pregnancy, since deficiency of one can impair the mother's or baby's capacity to benefit from the others.Breastfeeding is the natural and most healthy follow-up to a healthy birth. The World Health Organization and other experts recommend infants should get all their food from breast milk until 6 months of age. Breastfeeding also draws on the mother's B vitamin reserves, and lactating women frequently have B vitamin deficiencies as do many pregnant women. Supplementing with Smart Prenatal is a good idea all the way through pregnancy and the lactation period.
Folate, as Methylfolate not Folic Acid
Folate is the most researched nutrient for pregnancy, yet most prenatals and other multiples provide folic acid, a synthetic form of folate that is poorly utilized by our folate enzymes. Smart Prenatal supplies the smart folate choice – methylfolate, also called methyltetrahydrofolate or MTHF, MeF for short. This is the major form of folate in the blood, the brain and the rest of the body. MeF is also the predominant folate in breast milk. By supplying MeF this formula avoids the uncertainties and limitations associated with the use of folic acid in prenatal supplements.Folic acid is a synthetic chemical that the body can only poorly convert into active MeF, and it can partially block utilization of food folates. So Smart Prenatal directly provides MeF, which is efficiently absorbed, readily enters the brain and other tissues, and works smoothly with the body's folate enzyme systems. MeF is thoroughly documented for its importance in the baby's heart, brain and total body development.As a dietary ingredient, MeF is also the best folate choice because it bypasses a gene mutation that is very common in humans. Called MTHFR C677T, this mutation impairs the body's capacity to convert folic acid (or even food folates) into useful folates. By taking an MeF supplement the mother bypasses both this mutation and other less common mutations that also can impair her capacity to provide active folate to her baby.After birth, MeF continues to be extremely crucial for an infant's development. The mother's body strives to maintain its level in breast milk, but this can deplete her reserves and make her and the infant vulnerable to deficiency. By continuing to supplement with MeF she supports the infant's ongoing growth and development while protecting her own mood and wellbeing. MeF also helps mother and infant dispose of homocysteine, the metabolic product that can become brain-toxic.Smart Prenatal provides methyl not only as MeF but also as MeB12 (methyl-vitamin B12), which works closely with MeF to ensure optimal benefit.
Vitamin B12 as Methyl, Not Cyanide
This formula supplies the methyl form of vitamin B12 (MeB12), rather than the commonly used cyano-cobalamin, which contains potentially harmful cyanide. MeB12 metabolically conserves folate as MeF to optimize the mother's and baby's natural methyl metabolism. Adequate B12 in breast milk is also crucial for the infant's ongoing brain development, including for its nerve cells to continue to develop their electrical insulation ("myelination"), a prerequisite for healthy sensory and motor functions.Plants don't make vitamin B12, so vegetarians and vegans often have very low levels. Also, its absorption is highly complicated and vulnerable to blockade by over-the-counter and pharmaceutical medications. Supplementation during pregnancy and lactation is strongly indicated.The importance of the chemically simple methyl group (one carbon atom with three hydrogens) during early human development cannot be overstated. Methyl is vital for DNA production, maintenance and repair, and for the regulation of gene activity (epigenetics). Methyl is also vital for the brain to produce various major neurotransmitters and the sleep hormone melatonin, as well as for nerve cell membrane formation, electrical conduction and numerous other routine brain and body processes. The mother's brain and body, the placental tissues and the developing baby all need the high-grade methyl supplied by methylfolate and methyl-B12.
Thiamin (Vitamin B1)
Essential for the brain and other organs to process proteins, carbs, and fats, and for every one of our cells to make energy. Body thiamin reserves are normally very low, and are readily depleted by high-sugar diets, alcohol abuse, and various prescription drugs. Deficiency is common in pregnancy, affecting at least 25% of mothers in one study, and is linked to nausea and vomiting. Mothers low in thiamin may produce breast milk with insufficient thiamin for healthy infant development. Supplementation is highly indicated.
Riboflavin (Vitamin B2)
Essential for the body to process carbohydrates, fats and amino acids, and for energy production by the mitochondria, our cells' tiny powerhouses. Riboflavin is very important for the baby's healthy heart development. Best food sources are from animal sources and green vegetables. As with thiamin, mothers low in riboflavin may produce breast milk lacking sufficient supply for healthy infant development, and supplementation is highly indicated.
Niacinamide (Vitamin B3)
This is a fully active form of vitamin B3 that bypasses the uncomfortable skin flush linked to the niacin form of B3. It helps our cells' mitochondria make NADH (nicotinamide adenine dinucleotide, reduced), a high-energy nutrient fundamental to life's energy exchanges. NADH is also essential for a variety of enzymes that regulate gene actions. Niacinamide is very, very important for healthy development of the baby's brain, heart and all its other organs.
Vitamin B6, as Pyridoxine and Pyridoxal-5-Phosphate
This vitamin is vital for early brain development, and Smart Prenatal provides both of its best-absorbed forms. It is essential for at least 100 enzymes that help the brain make key neurotransmitters and help the body utilize carbs, fats, and amino acids derived from proteins. Vitamin B6 also is prominent in the disposal of homocysteine, a routine metabolic byproduct that can damage the brain. Vitamin B6 promotes conversion of homocysteine into very useful antioxidants. As a mother continues to breastfeed, both she and the infant can become very low in vitamin B6. Good B6 status is linked to healthy infant growth.
This vitamin is often found deficient during pregnancy and lactation. It is integral to at least 3 major energy-generating enzymes. Biotin is also vital for healthy gene regulation ("epigenetics"), for cell to cell signaling, and for healthy development of the brain, skin and body overall. Deficiency is increasingly common in the U.S. population. Alcohol intake can deplete this vitamin, as can intestinal absorption problems and anticonvulsant drugs. Supplementation with biotin is good nutritional insurance.
Pantothenic Acid (Vitamin B5)
This vitamin is crucial for the body to make energy. The brain cells need it not just for generating energy but to make amino acids, proteins and hormones, convert fats into useful fatty acids, and build cell membranes. Freezing, canning, and refining deplete this vitamin from foods. Pregnant and lactating women tend to have levels lower than recommended for good health, making B5 supplementation a good idea.
Choline - Methyl and More
Now classified an essential nutrient – practically a vitamin – choline is a rich source of vital methyl groups, and an important backup for the methyl that mother and baby get from methylfolate and methyl-B12. Human studies have confirmed choline is especially important for fetal heart development, and U.S. mothers with higher choline intake have healthier babies. For the brain and the body as a whole choline supports healthy production of acetylcholine, our most abundant nerve transmitter. Choline also backs up homocysteine regulation by folate and B12, and is also very important for the mother's liver health, for the placenta to function, and for high-quality milk production during lactation.
No longer regarded as just a bone vitamin, vitamin D is absolutely vital for the brain and all the organs. Very few people get enough sunshine to make optimal amounts of this vitamin, and deficiency is extremely common. The liver and kidneys actually convert vitamin D into a powerful hormone. This "Hormone D" regulates some 900 genes, many of which regulate healthy brain development via stimulating the formation of nerve cell connections (synapses), sensitivity to growth factors and response to the neurotransmitters acetylcholine and serotonin. This formula provides D3 (cholecalciferol), the most active vitamin D form—avoid taking D2, which can block vitamin D3's benefits.
This powerhouse vitamin is essential for the brain to develop and maintain its trillions of nerve cell connections (synapses). It is also crucial for the development of healthy vision, intestinal function, lung function, and immunity. As with other BrainMD products, this formula provides authentic vitamin A, rather than beta-carotene which many people have trouble to convert into functional vitamin A.
The well-functioning brain is equipped with very high levels of this vitamin. Besides being major antioxidant protection for the delicate brain tissues, this vitamin is a necessary cofactor for enzymes that regulate the major neurotransmitters acetylcholine, dopamine, and norepinephrine. The baby also needs C to make its nerve cell electrical insulation (myelin), and to ensure the structural integrity of the blood vessels that supply its brain cells. Breastfeeding mothers can become very low in vitamin C, and supplementation guards against this scenario.
This antioxidant vitamin is the most important protection for cell membranes, which are the most dynamic working parts of all our cells and make possible the brain's incredible connectivity. This supplement provides the full spectrum of alpha-, beta-, gamma- and delta-tocopherol vitamin Es present in a healthy diet. Vitamin E is also important to keep breast milk free of harmful free radical generation, and supplementation helps ensure it does not become depleted in the breast milk during the lactation period.
Vitamin K2, as Menaquinone-7 (MK-7)
This vitamin activates proteins that regulate calcium to support brain cell maturation, survival, and electrical conduction. Vitamin K proteins also regulate calcium in the other organs, and this MK-7 form is considerably more active than vitamin K1. It helps ensure calcium will form hard deposits only in the baby's developing bone, teeth and nails and not in the heart, blood vessels, brain and other soft tissues where they could cause harm. Vitamin K2 also promotes the baby's coagulation mechanisms needed for healthy wound healing.
Magnesium and Calcium
These two minerals are major essentials for human life. They have a “yin-yang” relationship, each helping balance the actions of the other. The brain, heart and other "soft" organs need just a small allowance of calcium for optimal function. Magnesium helps prevent excess calcium from causing tissue damage. Magnesium also powers as many as 300 enzymes (many of them involved in making energy), and helps the mother maintain healthy blood pressure and muscle tone for a healthy delivery. Magnesium deficiency is common in the United States. This formula supplies calcium and magnesium in their best-utilized forms.
This mineral is essential for the thyroid gland to make thyroxine and related hormones, which regulate the pace of development of the brain and other organs. The daily iodine requirement jumps during pregnancy and lactation. The World Health Organization sets a high priority on supplementation with iodine all the way through pregnancy and the breastfeeding period.
This mineral is essential for some 100 enzymes and other functional proteins. Zinc promotes healthy development of the brain, spinal cord, eyes, thymus gland and other immune organs, the intestinal tract, skin and other organs. It is overall essential for the baby's growth and development, and by the third trimester the mother's needs may be twice those of non-pregnant women. Breast milk levels are sensitive to the mother's zinc status, and often decline as breastfeeding progresses, making supplementation a very good idea.
Selenium is required by at least 25 proteins, including "front-line" antioxidant defense enzymes, key enzymes for regulating gene activity (epigenetics), and other involved in thyroid hormone production. Selenium proteins have global importance for the developing brain. Good selenium status in the first trimester of pregnancy is linked to good immune response at age 6 months, and to good language and motor development at 1 year of age.
Essential for enzymes that process amino acids, carbohydrates and cholesterol. Manganese also is required by a major antioxidant enzyme (SOD2, superoxide dismutase 2), which is critically positioned within the mitochondria to minimize potentially harmful oxygen free radical generation. SOD2 provides this crucial protection for the baby's brain and body both before and after birth. Adequate supply of manganese to the mother helps ensure a normal pregnancy.
Mother and baby need this mineral to efficiently use blood sugar for energy. This formula provides the picolinate form of chromium, known to be highly safe and effective.
Required by at least five detoxification enzymes that work very closely with the body's antioxidant defenses. Molybdenum enzymes help neutralize sulfites and bisulfites, potentially toxic substances often sprayed onto foods and used widely as food preservatives. Adequate molybdenum status helps the mother maintain her defenses against potentially toxic foodborne and environmental challenges.
As an "electrolyte" this mineral is important for maintaining healthy charge balance in the blood, other body fluids and even within our cells. It also works in balance with sodium to help the mother maintain healthy blood pressure, very important for a healthy pregnancy.
Coenzyme Q10 (CoQ, Ubiquinone)
This is a vitamin-like nutrient, termed "conditionally essential" because some people can't make enough of it and must get additional supplies from their diet. CoQ is fundamentally required for the generation of at least 90% of the mother's and baby's energy by their cell mitochondria. It is also a potent antioxidant that protects both baby and mother. Good CoQ status during pregnancy is associated with healthy birth outcome. Its levels in milk decline as lactation continues, making supplementation prudent. Few prenatal supplements provide CoQ.
Lutein and Zeaxanthin
These two carotenoid nutrients are practically vitamins since the body cannot make them. They are unique antioxidants, highly concentrated in the retina of the eye to protect against harmful free radicals generated by light. Recent research found they are also concentrated in the brain where they probably facilitate healthy visual information processing and other higher brain functions. Adequate intakes of lutein and zeaxanthin support healthy vision development. Breastfeeding can deplete their supply to the infant, making supplementation a prudent choice.
This mineral supports healthy brain function. It also supports the utilization of vitamin D and magnesium, both very important for healthy brain development.
|Serving Size 4 Capsules
Servings Per Container 30
|Amount Per Serving||%DV|
|Vitamin A (as retinyl palmitate)||4000 IU||80%|
|Vitamin C (as ascorbic acid)||500 mg||833%|
|Vitamin D (as D3, cholecalciferol)||2000 IU||500%|
|Vitamin E (as d-alpha-tocopheryl acetate)||30 IU||100%|
|Vitamin K (as K2, menaquinone-7, MK-7)||80 mcg||100%|
|Thiamin (Vitamin B1) (as thiamin HCI)||50 mg||3333%|
|Riboflavin (Vitamin B2)||50 mg||2941%|
|Niacinamide (Vitamin B3)||50 mg||250%|
|Vitamin B6 (as pyridoxine HCI and
|Folate (as Quatrefolic® methylfolate,
5-methyltetrahydrofolate, glucosamine salt)
|Vitamin B12 (as methylcobalamin)||500 mcg||8333%|
|Biotin (as d-biotin)||500 mcg||167%|
|Pantothenic acid (as d-calcium pantothenate)||75 mg||750%|
|Calcium (as pantothenate, citrate)||50 mg||5%|
|Iodine (as potassium iodide)||150 mcg||100%|
|Magnesium (as malate, citrate, and glycinate)||60 mg||15%|
|Zinc (as glycinate)||30 mg||200%|
|Selenium (as high-selenium yeast)||105 mcg||150%|
|Manganese (as glycinate)||2 mg||100%|
|Chromium (as picolinate)||500 mcg||417%|
|Molybdenum (as sodium molybdate)||75 mcg||100%|
|Potassium (as citrate)||70 mg||2%|
|Choline (as bitartrate)||275 mg||†|
|Coenzyme Q10 (ubiquinone)||50 mg||†|
|Mixed tocopherols (Vitamin E)||30 mg||†|
|Lutein, carotenoid||3 mg||†|
|Zeaxanthin, carotenoid||300 mcg||†|
|Boron (as glycinate)||1.5 mg||†|
|†Daily Value (DV) not established.|
Vegetable cellulose (capsule), microcrystalline cellulose, silicon dioxide, magnesium stearate.
Free from milk/dairy, gluten, wheat, eggs, corn, sugars, or artificial coloring or flavoring.
SUGGESTED USE:Take 4 capsules daily after meals.
Frequently Asked Questions
We strongly urge all mothers to complement Smart Prenatal with BrainMD's Omega-3 Power, which supplies the high intakes of EPA and DHA both mother and baby need. Adequate EPA and DHA during pregnancy and breastfeeding are indispensable for the long-term optimal development of the brain, eyes, heart, blood vessels and other organs. You can purchase both together and save as a bundled price soon!