NeuroVite Plus

50 vitamins, minerals and plant extracts specially formulated to deliver the whole-body, brain health boost you need!


NeuroVite Plus

NeuroVite Plus

The first and only daily multivitamin created through the clinical experience of brain health expert Daniel G. Amen, MD

NeuroVite Plus combines more than 50 nutrients and plant extracts in their most active forms to give you whole body-mind nutrition in a way that drugstore multivitamins cannot do. It contains three of Dr. Amen’s hand-selected proprietary high-nutrient blends:

  • The Brain Boosting Blend of clinically researched brain health nutrients.
  • The Fruit and Vegetable Blend with the antioxidant equivalent of 5 servings of fruits and vegetables.
  • The Digestive Enzyme Blend to support digestive health, metabolize foods and support your natural intestinal balance—which is critical for a healthy brain.

NeuroVite Plus Delivers Vibrant Health and Wellness in 5 Ways!

  1. Nourishes your body’s cells, tissues and organs – NeuroVite’s wide range of nutrients gives every part of your body the nutrients it’s hungry for.
  2. Promotes optimal brain function – NeuroVite’s high levels of important phytonutrients help sustain our intensely active brain cells.
  3. Supports the health of major organ systems – with lutein and zeaxanthin for the eyes, hesperidin for the circulation, and resveratrol for the heart.
  4. Protects against free radical damage with an array of antioxidants including vitamin C, vitamin E, alpha lipoic acid and CoQ10.
  5. Easily absorbed and tolerated, due to the very careful selection of its ingredients and its content of digestive enzymes.


Piece of mind that our bodies are being supported with necessary nutrients.

My husband and I have been taking neurovite plus and can feel a difference with our energy and vitality.

I thought I would be disappointed

Multiple vitamins always make me feel a little nauseated and I don't like taking them. So I only ordered one bottle from Amen Clinics, expecting to be disappointed. What a surprise, to find that NeuroVite makes me feel really good, pretty quickly. They don't bother my tummy and my thinking is immediately more clear. This stuff really works.

A vitamin of the highest quality

I’ve been taking NeuroVite Plus for a year, and my energy, well being, and gratitude for life has tremendously improved. Dr. Amen, thank you for your faithfulness on helping and teaching people like me to take care of our temple. God bless!

Best vitamin!

Best vitamin we've ever had! We take it every day. Thank you.

My nutrition insurance

I try to have a healthy diet, but I feel I need some insurance that I am not missing essential nutrients. These are expensive, but being ill is expensive. I like that they are formulated with real ingredients, not synthetics.

I have truly seen a difference for my daughter, and she notices the difference even after missing one day.

This has made a significant improvement in my daughter’s mental state and helps her cope with her worries. I too have started but only taking half the dosage. This was just a trial period for us and we are happy with the results. Have ordered more and hope it continues to improve. Anxious to get more, just sorry that you have to pay extra to get the item faster, otherwise it takes almost 2 weeks.

Best product I have taken to date.

I feel so much better and alert on NeuroVite Plus. I can feel the potency as well.

Give it all the stars

I am basically retired, but I occasionally accept temporary assignments. On my last assignment I served as a team lead. I credited NeuroVite for having the clarity and decisiveness to function at that level.

I feel so much better

I've been taking NeuroVite Plus for a month now and all I know is that I just feel better all around. I'm sleeping better with clearer thoughts and a calmer yet more energized day. Amen, Dr. Amen!

Based on all the other reviews, I must be a fluke. But I don't trust them.

I switched to this vitamin based on the rage reviews. Since taking it, about a month now, I cannot think clearly. It is very scary not to trust your mind. Also, my eyes became red. I thought they were just blood shot. Turns out they have this issue which I don't remember the name. All this started when I started taking these pills. If your mind and eyes are affected after taking these, please stop.

excellent multi vitamin

Definitely noticed a change in energy levels and just feeling good! I am only taking 3 capsules per day - 2 in the a.m. and 1 at dinner. The vitamin b-12 was affecting my sleep. Reducing to one capsule at dinner did the trick. Highly recommend!

So happy with results

I started taking this product 4 weeks ago. I started with one (1) capsule a day and noticed a positive difference. I increased intake by one (1) capsule per week, now taking the recommended four (4) capsules per day. I am totally convinced this product has made a remarkable difference in my total being! I've had the most energy, that I'm now cooking dinner after a full day's work, began walking in the mornings and I'm able to function more efficiently at work. My typical day USED to be: struggle after a few hours of sleep, being tired while I readied myself for work, went to work and didn't perform at my maximum, returned home only to lay on the couch because of fatigue and was eating out almost every night because I was just too fatigued to prepare home cooked meals and definitely couldn't clean up after dinner. My husband has expressed joy in seeing me much more energetic and with a positive attitude. Thank you, Dr. Amen!!! I love this product!

Love, LOVE This

Whatever is in this, and there is a lot, I really like it. This probably sounds strange, but I look forward to taking it in the same way I look forward to a smoothie. I just know it is doing good things for my mind and body. After taking this and a few other products for a few months, I retook my brain assessment and found that my score was different by a few points.


The best thing I have ever done for me. Excellent product! Thank you!!!!

I take this supplement everyday after a meal.

I began NeuroVite Plus before I went to visit the Amen Clinic in Orange County. I found this supplement to be well-rounded and gave me a boost.
I highly recommend this supplement to everyone.

Complete multivitamin

Has just about everything you need & more in a multivitamin. Great product.

Excellent comprehensive supplement!

This is an excellent supplement and very comprehensive. Meets my needs and promotes a strong sense of well being. I like that it offers additional ingredients to nourish the brain. Thank you!

Healthy immune function with my daily NeuroVite Plus multi-vitamins

I'll be honest, I'm not one of those who can tell a major difference in my energy levels or how I feel overall when I take, or do not take my multivitamin. That said, I've now been using NeuroVite Plus for a year and I can say that I have avoided getting sick, even with all of my family (2 kids under the age of 6 and my wife) have been absolutely miserable. I wish they were concentrated into just two pills (one in the morning and one in the evening) but I have my reminder app setup and take them mid-morning and early afternoon and have been doing great. Thank you, Dr. Amen!!!


When I began taking NeuroVite Plus, it was as a part of the Brain & Body Power mix, which is also an excellent product. I then tried NeuroVite separately while experimenting with other Amen Supplements. I noticed immediately the difference when I ran out of it, having to wait a few days for the reorder (not on auto-ship). All I can say is there is quite a difference in all aspects - thinking clearly, gut, stamina, etc., which became very clear to me after running out. I have to be cautious regarding any supplement I take, especially orally, due to Crohns, Sjogdrens, Lupus and much more in the immune & inflammatory areas. NeuroVite is the only multi-supplement this body can handle. It is very effective. Try it.

Highly recommended

Excellent product! The cost of this product is a bargain when comparing the cost of buying them separately. The combination is very effective.

Top notch multivitamin!

I like the fact that this multivitamin has brain boosting qualities and many other ingredients to maintain a healthy lifestyle.

Best Multivitamin, period.

By far the best multivitamin supplement on the market. Take a trip to GNC/and or Vitamin Shoppe, you won't find anything this supreme!

My go to multivitamin! (Exceptional supplement)

Undoubtedly the most potent multivitamin on the market, period.

Great vitamins and minerals in this Multi vitamin

I was looking for a good quality multi vitamin and was not sure with the majority of other products on the market. Reading, watching the video and comparing the labels assisted me to get the best product. Mentally and physically my body is getting better vitamins and minerals that I was lacking.

It is the best thing I have ever done for my low mood, lack of focus, and lack of motivation.

It is the best thing I have ever done for my low mood, lack of focus, and lack of motivation. I take this in combination with Focus and Energy, fish oil, and 5HTP at the recommendation of Dr. Chapek when I visited at the Amen clinic after getting a SPECT scan. I live in Costa Rica, and was desperate for help. When I learned about what the Amen Clinics do I sold my car and used up every penny I had to get to the US and pay for the visit. It was worth it down to the last penny. The clear understanding attained through the SPECT scan was exactly what I was looking for and the supplements from the Amen clinic really work. It's sometimes difficult to get them down here so I have tried others with limited success. If I run out of them my wife notices after a few days. Getting proper nutrition, good exercise, and good supplements has helped me so much more than anything I have taken in the past. I have been benefiting from these supplements for about 7 months now, and I'm so thankful that the Amen Clinics were able to give me the help I needed.

Really works

I took this for quite a while and then decided that to save money I would go to a cheaper, though high-quality supplement (sold only through doctors). I could not believe how different I felt. The difference was quite amazing. Needless to say, I ordered more NeuroVite.

Highly recommended!

Been taking this product for a couple of years. High quality supplement!

Best I've ever had

One of the best vitamin supplements I've ever head. The difference was immediately noticeable. I could focus, had more energy and could get through my workday without my usual sense of being drained and exhausted.

Packed with supplements in one capsule. A great deal

Comprehensive vitamin mineral supplement. I am taking twice a day and starting to feel more energy. Recommended for my brain type 1.

More than just a multivitamin

I've been on this product for two years and I love it! It's got all the goodness of a multivitamin plus ingredients specifically designed to help your brain function better. It's helped me so much.

The Brain warriors way!

Let's face it, even the most structured individual has a difficult time getting all the nutrients he or she needs. This SUPER multivitamin fills the gap for us health conscious doers! Superb supplement!

Take care of your brain and your brain will take care of you!!!!

I feel confident that I'm giving my brain what it needs for a lasting brain health! As an Occupational Therapist who practices brain training therapy I know that what you do now will affect the function and vitality of your brain for the rest of your life. I like to say to my clients.......Take care of your brain and your brain will take care of you!! Thanks Dr Amen for making it easier to care for my brain.

Great Product in a Great Regimen

This has been working great for my son in combination with some other products from BrainMD. This, Attention Support, and Omega 3 seem to be doing a great job for him. We have noticed it, and his teachers have called us to find out what we are doing because he has improved THAT much!

A product I trust

I trust that this blend developed by Dr. Amen is a good choice. I like his no nonsense attitude. Vitamins are only as good as the company behind them. There isn't really any way to measure their effectiveness.

Best vitamin ever

I am very satisfied with my purchase. My body and mind feels great. I can feel the difference the days that I forget to take the vitamin.

Very helpful. It's kept me from getting sick.

My body has been through a lot of trauma and stress this year, and with all this stress I should be sick continually. NeuroVite Plus has given me an advantage by keeping me healthier than I would be without it. My immune system seems stronger since I started taking NeuroVite Plus a couple months ago. It has also really helped my cognitive function.

I love NeuroVite.

I am loving NeuroVite. I am noticeably more energetic, plus I feel confident that I am practicing good brain health by taking this product.

Game changing supplement

This supplement changed my life, I'm very satisfied with the quality. I can feel the difference when I miss a dose. Definitely will recommend to family and friends!

Great vitamins that provide energy

Love these vitamins! My husband & I both use them. Gives you energy without feeling jittery. They have everything we need!

has everything i needed

great product

Best Multivitamin I have tried

I was using NeuroVite Plus and ran out of it. I live in Australia and found it hard to get so decided to try another supplement that a friend of mine was a distributor for. I used her product for a month and didn't like the way I felt. I was always tired and had no energy. I have since switched back to NeuroVite Plus and what a difference it has made. My energy level is back and I feel so much better. I highly recommend this product.

Works great!

I'm amazed what these vitamins have done for my life. It's pretty cool.

Love this

The balanced amount of vitamins & minerals works well for me & doesn't give me any lingering aftertaste or digestion problems like some other vitamins have in the past. Seems to help with my energy level.

Great Multivitamin for Anyone!

This is a great multivitamin. I used to take a bunch of different vitamins but have now cut those out and just take this one. My daughter and I both take it every day!

Great product

I have more thoughts after taking this vitamin. I feel like my memory is better and my thinking more clear. I love it!

Getting to the heart of health with these vitamins and minerals!

My husband and I have been taking the NeuroVite in our daily routine in the Mind and Body packages. I know we are feeling better and stronger as we start making decisions for Brain and Body health for the last several months. Adding these to a healthy daily routine is HUGE in sick body/brain recovery!

This is the best multivitamin, very complete. Vitamin D level is perfect

Love the combination of vitamins and minerals in this vitamin. Also the amount of vitamin D for me is perfect.

This is the perfect supplement for me.

This is a great supplement. It makes me more energetic and gives me a clear mind. This is a true standardized supplement that gives me all the minerals that I need without fillers. With this supplement, I don't feel that I need to take other vitamins because they are all in this supplement.

Love it!

I love that it is a complete multivitamin.


I have taken this, either alone or as part of the Brain & Body Power packet, for several months now. I have been able to eliminate almost all of my other supplements as they are included in this multiple. Thanks

Best multivitamin on the market!

This multivitamin is so complete. You know exactly what nutrients and vitamins you're getting and you can trust what you're getting!

Love the dosage and effectiveness. Gives me energy.

Best vitamin out there.

Worth the money

Took this for about a month and to save money went back to my old multi. After a few days, I felt tired and listless. Could not believe the difference! Would like to point out that I only take high quality supplements and my old multi is a quality product. Worth the money!

Now THIS is a multivitamin!

I used to take about fifteen different vitamin and mineral supplements a day in order to "mind the gap" that my commonplace multi left behind. Now I just take this, along with the omega 3, probiotic, and GABA. The capsules twist open so the contents can be poured into a beverage, smoothie, yogurt, etc. - for those of us who have difficulty swallowing pills. My mornings are much easier now, and I'm much more motivated to take my supplements.

Great product.

My son and I started taking the NeuroVite and all I can say is that so far we feel great

Best multivitamin there is

This multivitamin has more vitamins and minerals and the highest mgs than any other multivitamin. It is a superb product. It is worth the price. There is no other multivitamin like it.

I'll never buy a multivitamin from the pharmacy again !!

I felt an immediate difference after taking it. I've been looking for a multivitamin of this caliber.

Confident...Sense of Wellbeing!

I know this is a great product supplying what I need...confident in the wellbeing I am feeling!

Great product

Neurovite Plus has helped me feel more balanced. I love that Neurovite Plus contains so many quality nutrients for the brain and body.

The best multivitamin I have ever taken!!

The best multivitamin I have ever taken!! I don't feel sick after taking Neurovite like other multivitamins i have taken in the past. I feel overall more alert and strong.

Good multivitamin

Really good multivitamin. I can tell when I do not take this. It gives me energy to get through my day.

Great product.

Great product.

Your body will thank you!

Hands down, the best multi I've ever taken. I feel alive and energetic, even when I don't get ample sleep. Your body will thank you!

A fundamental support for my brain functioning

It's amazing for me, because it supports my thought processes at a fundamental level, supporting the other supplements I'm taking, like Focus & Energy and Everyday Stress Relief.

High Quality Ingredients-Increased Energy and Well Being

I have reordered NeuroVite Plus 4 times now and have been very pleased with my overall health since taking it. I know, based on the high quality ingredients, that this product has contributed greatly to my increase in energy and improved wellbeing.

Love this product and will continue to use it daily. Seems to cover so much our bodies need as we age.

This vitamin has so many right on ingredients of which 3 I was taking individually. Now that I am taking this, I have dropped those 3 and so glad bc not having to swallow 3 more pills. This has all the essentials along with the brain boosting blend, fruit and veggie blend and the digestive enzyme blend. This one product seems to cover everything and I seem to be more alert and have more energy too. Directions say to take 4 a day, I only take 2, but still feel its effects. As I work some others out of my regime, I will get up to the daily requirements for this one.

Great supplement.

Started this product a few weeks ago, and have noticed increased energy throughout the day. Normally felt exhausted by early afternoon. Now, I no longer feel like I need a nap.

take with confidence of quality

I use Neurovite Plus - now for some time. It is a great blend of vitamins and minerals naturally occurring- the best! I think having these nutrients daily keeps me healthy and active. I trust Dr. Amen to have a quality product. You hear about many supplements that are tested and do not contain the nutrients. I do not worry about poor quality in these products. I take them with confidence.

The physical and mental boost I need for a very stressful life

This is a great product. I have to admit that I did not realize how much I needed these vitamins until I thought I could go off them for a while. It was then that I noticed how much they really help me. Let's just say it's the difference between being a total slug on the couch and actually being able to get things accomplished. I am a mother of a 6 year old autistic boy and the stresses and strains of such a situation can drain me completely, both physically and mentally, to the point where getting up to do even the simplest of tasks was almost more than I could stand. These vitamins give me the boost I need to keep me going physically and mentally.

Good for the body

Neurovite Plus is very nice supplement for your body system, a trial will convince you


I've been taking these for awhile and have really noticed how much better I feel.


I've been taking this as a part of the brain power basics. I absolutely love it!


It is worth the price. I have more energy and focus since I started taking these vitamins 8 months ago.

Looks Great

This looks like the most complete multi-vitamin plus that I have found so far!


I love NeuroVite Plus! I can't say enough about what a perfect multi that does so much more. I feel better, sleep better!

High quality nutrition

I am very happy with Neurovite because it is a complete supplement for my daily nutrition and I don't have to purchase anything else. I had been spending as much money on different supplements as I spend with Neurovite! I have more energy and I feel overall better. It has helped with my chronic depression and I feel more alive! I love my Neurovite!

my dad is diabetic and feel improvement

I bought this product for my dad. He is taking neurovite plus for 30 days already. It feels calmer, better sleep and sleep longer (before he felt no sleep and needed sleeping pills, but now not anymore). It feels more energetic, more glad. Feels less pain in the body, and headaches are almost gone, and the ones he have are softer
I see that now it is easier to talk with him, his mood is more stable. He loves his neurovite.
My Mom also take it, and she feels really good, more active, with more energy, much better in general, and also she doesn´t feel sleep during the day anymore and sleep well during the night
Dr. Amen thanks for bringing happiness to my parents

Great MultiVitamin

I take this every day, it is great, high quality, has everything I need. My kids are able to swallow too which is helpful, however, I purchase the Kid's Neurovite for them, as they love the taste.

For energy and overall well being

My whole family takes this every day and we have all noticed a huge improvement in energy, digestion and as an added plus food cravings have decreased. Great product.


I have used these for a year. They seem to work great and help me stay clear minded.

So much improvement!

I use NeuroVite Plus with Serotonin Mood Support, GABA Calming Support, and Omega-3 Power and I saw so much improvement in just a week. I am able to sleep better, control negative thoughts better, and think more clearly. I don't have the anger outbursts I used to have and I just have a better mood in general.

My son is doing great on this!

We have our son on this and Neuro 5-HTP and we see such a difference for him. He is much calmer, more focused, staying on task more, has greater organization, and no longer angry. God bless the Amen Clinics!

This is a great product!

I feel so much better and have more energy since being on this!

My body/mind loved it.

I wish I could afford this all the time but on my fixed income I can't but when I did take it noticeably different.

Best Mulit

This is the best quality and most complete multi I have found. Doesn't hurt my stomach. Feel better all around when I take it.

NeuroVite Plus

I am a fan of Dr. Amen. After reading his book "Change your brain Change your body" I lose 15 kilograms overweight. After that, my father repeated same experience.
I started to use NeuroVite Plus recently and I will continue.

Just what I needed!

This was just the multi vitamin I needed!

thankful for this

Our daughter's focus issues were helped greatly by this supplement almost immediately. We will continue to buy this for her.


I was previously taking another specialty product recommended by my specialist. That product was substantially more costly. When I found this supplement, I had the specialist review the ingredients and she agreed I should try it. The product performed at least as well, but an unexpected benefit occurred. This might not be the same for anyone else, but it kept my Diabetes 2 under control.

I ran out of the Neurovite Plus and then started noticing my glucose readings were substantially higher, like before. I didn't think of any correlation until I reviewed my records and realized the correlation between the dates I was on the product, and the dates I had run out of the product. I don't intend to run out of this product again!

Great Multivitamin!

This is a very complete vitamin that focuses on brain health. Others I have bought from the big box retail stores have made me jittery or made my attention issues worse. I don't feel any negative side effects and I take this with my daily meds. My psych even recommended it to help fill nutritional gaps and overall brain health.

excellent product

At 70 yrs old I needed more energy and improvement in memory. After 4 weeks I noticed a significant improvement. I definitely could find my car faster in the parking lot.

reordering -- it's worth the price

As other reviewers have said, it's noticeably, immediately beneficial to clarity, energy, focus. It's the best new supplement I've added to my regimen in... well, forever! Glad I discovered it.

NeuroVite Plus

I have been using this supplement in the past 3 weeks and I am amaze the quality that work. However I am not happy about the price but I appreciate the quality.

simple way to get my veggies

simple way to get the nutrients I need to take. not happy about the price but I appreciate the quality

NeuroVite Plus

I recently order a bottle of NeuroVite Plus and can not wait to give it a try.


This is the first vitamin I've ever taken that I can actually feel working! On the days I skip it, I can tell I don't have near the clarity of mind that I do when when I take it... so plan to put on auto-ship!. Thank you Dr. Amen for finally giving us something that is worth the money!

Neurovite Plus review

At 77 years old I know when I take this vitamin I have much more energy during the day. I will not be without it again.


This supplement is helping me with focus and brain energy already and I've only taken it for a few weeks!

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Ingredients & Facts


  • Vitamin A
    This powerhouse vitamin is crucial for the intestinal tract, the eyes and vision, lungs, healthy fetal development and a powerful immune system. NeuroVite Plus omits beta-carotene, which some people have trouble converting to vitamin A.
  • Vitamin C
    Vitamin C is well known as a potent antioxidant that protects the body against “free radicals” and other toxins, helps the body conserve other antioxidants, and is fundamental to healthy immunity. But it is also an essential cofactor for enzymes that make neurotransmitters, conduct detoxification, and synthesize collagen for the gums, joints and other connective tissues of the body.
  • Vitamin D3
    Superior to D2, vitamin D3 is called the “sunshine vitamin” because the skin can make it. Unfortunately many people aren’t getting enough sunshine and vitamin D deficiency is widespread here and around the world. The body transforms it into a powerful hormone for the brain, heart, circulation, immune system and other organs as well as for bone strength. This supplement provides a generous allowance of D3 to help ensure its numerous essential uses throughout the body.
  • Vitamin E
    Vitamin E is the major antioxidant protector for cell membranes – where our most dynamic enzyme assemblies are located. This supplement provides the full spectrum of alpha-, beta-, gamma- and delta-tocopherol vitamin Es present in a healthy diet.
  • Vitamin K2
    NeuroVite Plus contains vitamin K2 as menaquinone-7 (MK-7), the most potent K vitamin. Beyond its importance for the healthy processes of blood coagulation, K2 is absolutely required for cementing calcium into bone and for keeping calcium appropriately low in the body’s soft tissues.
  • Thiamin (Vitamin B1)
    Vitamin B1 is essential for the body to make energy and metabolize amino acids and blood sugars. Thiamin is especially important for managing dietary carbohydrates, which are linked to “high-calorie malnutrition.”
  • Riboflavin (Vitamin B2)
    Riboflavin is an essential cofactor for various enzymes that produce energy. Our cells also need it to maintain their DNA and to regulate healthy gene activity. Riboflavin is also essential for an enzyme that maintains glutathione, the body’s master antioxidant.
  • Niacinamide
    Niacinamide is a fully active form of Vitamin B3 that does not cause the uncomfortable niacin skin flush. Niacinamide is centrally involved in the generation of energy by mitochondria, our cells’ energy generators. This vitamin is easily depleted by excessive alcohol intake and by smoking.
  • Pantothenic Acid (Vitamin B5)
    Pantothenic acid is essential for our cells to produce coenzyme A, which they need to make amino acids, proteins and hormones, metabolize fats into useful fatty acids, and to build cell membranes. Freezing, canning, and refining deplete this vitamin from foods.
  • Vitamin B6
    Vitamin B6, as pyridoxine and pyridoxal-5-phosphate, is essential for at least 100 enzymes that help the body utilize amino acids, fatty acids, and carbohydrates. It is vital for early brain development and the actions of various neurotransmitters, as well as for supporting the body’s innate antioxidant defenses.
  • Folate
    Folate as methylfolate (methyltetrahydrofolate or MTHF) is the most active form of this vitamin. MTHF supplies methyl groups, which our cells need for making and repairing DNA, and for regulating DNA activity within our genes. The brain specifically requires MTHF to make neurotransmitters, the myelin insulation for nerve cells, and the sleep hormone melatonin. MTHF helps recycle the metabolic product homocysteine to prevent it from building up to toxic levels. A common gene mutation (C677T) impairs the body’s capacity to convert food folates or folic acid into MTHF.. By directly providing MTHF, NeuroVite Plus avoids the limitations of the many products that carry synthetic folic acid. MTHF does what folic acid cannot do: bypass the metabolic roadblock imposed by C677T.
  • Vitamin B12
    Vitamin B12 as methylcobalamin or methyl-B12, is required along with MTHF by key enzymes that manage methyl metabolism and recycle homocysteine. Methyl-B12 is fully activated and is superior to cyano-B12 (cyano-cobalamin), which contains potentially harmful cyanide and is found in many multivitamins. The high level of methyl-B12 in this formula helps ensure its efficient delivery to the tissues.
  • Biotin
    This B vitamin is also vital for DNA structure and for healthy gene activity, besides being essential for energy. Biotin is actually built into the structure of several enzymes that our cells’ energy generators (the mitochondria) use to make energy. Biotin deficiency is relatively common in the U.S. population.

Essential Minerals

  • Calcium and Magnesium
    These two minerals have a “yin-yang” relationship, each helping balance the actions of the other. Magnesium is required by at least 300 energy enzymes, yet almost half of all Americans may be deficient in this mineral.
  • Iodine
    Iodine is essential for the thyroid hormones that help set the pace of our metabolism and overall activity level.
  • Zinc
    Zinc is essential for DNA integrity, the “front-line” antioxidant enzyme superoxide dismutase, prenatal and postnatal childhood development, sexual maturation, behavior, immunity, skin quality, and hair renewal.
  • Copper
    Copper works with zinc in the superoxide dismutase antioxidant enzyme, and is essential for the brain to make neurotransmitters, as well as for a healthy circulation.
  • Selenium
    Selenium is required by at least 25 enzymes and other “selenium proteins.” Among these are the glutathione peroxidase enzymes that defend against free radicals, and a variety of other enzymes that sensitively regulate gene activity, thyroid hormone production, protein synthesis, cell-to-cell communication, muscle development, and immunity.
  • Manganese
    This mineral is essential for one of the superoxide dismutase enzymes, located within the mitochondria to neutralize oxygen free radicals as they are generated. Manganese is also needed for the metabolism of cholesterol, carbohydrates, and amino acids, and to produce bone matrix components called proteoglycans.
  • Chromium
    Chromium is essential for healthy blood sugar metabolism. This supplement provides the picolinate form, which is very well absorbed, helps in coping with carbohydrate cravings, and supports healthy mood management.
  • Molybdenum
    NeuroVite Plus provides a generous allowance of this mineral, which is required by at least 5 detoxification enzymes, especially to neutralize sulfites and bisulfites, potentially toxic substances that are generated by the body’s normal sulfur metabolism. Sulfites and bisulfites are common environmental pollutants and are often sprayed onto foods and added into wines, vinegars, even into medical products as preservatives.

Other Nutrients

  • Choline
    This vitamin-like essential nutrient supports the body’s production of acetylcholine, our most abundant nerve transmitter. It also supplies methyl groups for healthy DNA gene regulation, and is crucial for healthy liver function.
  • Lutein and Zeaxanthin
    These two vitamin-like carotenoid antioxidants are necessary for vision and eye health. Recent clinical studies suggest they also contribute to healthy brain function.
  • Resveratrol, Pterostilbene
    Resveratrol is under intensive research and is known to promote healthy heart muscle function. Pterostilbene is chemically related to resveratrol and supports circulatory health.
  • Hesperidin Flavonoid Complex
    This complex provides powerful antioxidants known to protect the delicate blood vessel walls.
  • Boron
    Boron supports cell energetics, especially for bone, joint and brain health.
  • Silicon
    Silicon supports healthy bone and connective tissue renewal and may also be required for healthy immune response.
  • Fruit and Vegetable Blend

    Dr. Amen created this proprietary blend to help ensure his patients receive the antioxidant and other, diverse biochemical benefits of plant nutrients (phytonutrients). This unique blend includes concentrates of wild blueberries, broccoli sprouts, tomatoes, spinach, acai, carrots, strawberries, and alfalfa sprouts.

  • Proprietary Brain Boosting Blend

    Dr. Amen developed this potent blend to further promote optimal brain function and help the aging brain.

    PhosphatidylSerine (PS), the brain nutrient best documented for improving memory, is most abundant in the trillions of synapses where the brain’s nerve cells interconnect.

    Acetyl-L-Carnitine (ALC) fuels energy generation by the mitochondria, but also supplies acetyl groups that help the brain make the important neurotransmitter acetylcholine. ALC and its acetyl groups are also used by brain cells to help regulate their gene activity.

    Alpha-Lipoic Acid (ALA) is a major energy cofactor, naturally built into the structure of three key energy enzymes that are very active in the brain cells but also active in every other cell of the body. ALA is also a powerful antioxidant.

    Coenzyme Q10 (CoQ10) is an essential cofactor for energy generation in the body, via the mitochondria’s electron transfer enzymes. These are constantly at work in all our cells but are most active in the brain to supply its huge energy demands.

  • Digestive Enzyme Blend

    Dr. Amen put together this full spectrum of digestive enzyme support with Lipase, Amylase, Lactase, Cellulase and Protease to help keep our digestive and other gut functions healthy.

Supplement Facts
Serving Size 4 Capsules
Servings Per Container 30
Amount Per Serving %DV
Vitamin A (as retinyl palmitate) 5000 IU 100%
Vitamin C (as ascorbic acid) 200 mg 333%
Vitamin D (as D3, cholecalciferol) 2000 IU 500%
Vitamin E (as d-alpha-tocopheryl acetate) 30 IU 100%
Vitamin K (as K2, menaquinone-7, MK-7) 45 mcg 56%
Thiamin (Vitamin B1) (as thiamin HCI) 50 mg 3333%
Riboflavin (Vitamin B2) 50 mg 2941%
Niacinamide (Vitamin B3) 50 mg 250%
Vitamin B5 (as d-calcium pantothenate) 50 mg 500%
Vitamin B6 (as pyridoxine HCI and
25 mg 1250%
Folate (as Quatrefolic® methylfolate,
5-methyltetrahydrofolate, glucosamine salt)
400 mcg 100%
Vitamin B12 (as methylcobalamin) 500 mcg 8333%
Biotin (d-biotin) 500 mcg 167%
Pantothenic acid (as d-calcium pantothenate) 50 mg 500%
Calcium (as pantothenate, citrate) 20 mg 2%
Iodine (as potassium iodide) 75 mcg 50%
Magnesium (as glycinate and malate) 50 mg 12%
Zinc (as glycinate) 20 mg 133%
Selenium (as high-selenium yeast) 200 mcg 286%
Copper (as glycinate) 500 mcg 25%
Manganese (as glycinate) 5 mg 250%
Chromium (as picolinate) 200 mcg 167%
Molybdenum (as sodium molybdate) 50 mcg 67%
High-gamma mixed tocopherols
(Vitamin E)
30 mg
Choline (as bitartrate) 25 mg
Boron (as glycinate) 1.5 mg
Silicon (as horsetail extract) 3 mg
Lutein, carotenoid 3 mg
Zeaxanthin, carotenoid 300 mcg
Hesperidin flavonoid complex 20 mg
Resveratrol (as trans-resveratrol) 10 mg
Pterostilbene (as pTeroPure™ trans-pterostilbene) 20 mcg
Fruit & Vegetable Blend
(wild blueberries, broccoli sprouts, tomato, spinach, acai, carrot, strawberry,
alfalfa sprouts)
140 mg
Proprietary Brain Boosting Blend
(acetylcarnitine, alpha-lipoic acid,
phosphatidylserine/PS, coenzyme Q10/CoQ)
575 mg
Digestive Enzyme Blend
(lipase, amylase, lactase, cellulose, protease)
30 mg
†Daily Value (DV) not established.
Other Ingredients: Vegetable cellulose (capsule), microcrystalline cellulose, spirulina extract (for color), magnesium stearate.

Free from milk/dairy, gluten, wheat, eggs, corn, sugars, or artificial coloring or flavoring.

SUGGESTED USE: Adults take 4 capsules daily after meals (up to 8 capsules under the supervision of a nutritionally-informed physician). Children ages 9-18 take 1 capsule per 40 pounds of body weight, not to exceed 4 capsules daily. Not intended for children under 9 years.

Dr. Amen talks about NeuroVite Plus

Dr. Amen discusses his most potent nutritional weapon for a top-performing body and mind

The Science


  • Vitamin A
    Vitamin A is an essential nutrient with roles in supporting the immune system and brain development. Its metabolite is important cognition, behavior and neuroplasticity.
  • Vitamin C
    Vitamin C is an antioxidant that is required for over 300 metabolic functions in the body, including tissue growth and repair and adrenal function. It stimulates procollagen formation, enhances collagen synthesis, and stimulates alkaline phosphatase activity, a marker for osteoblast formation. Vitamin C’s antioxidant activity diminishes lipid peroxidation, oxidative DNA damage, and oxidative protein damage. It has been shown to reduce levels of low density lipoproteins and increase high density lipoproteins, which may aid in preventing atherosclerosis. Vitamin C can prevent the formation of carcinogens in foods and in the gastrointestinal tract. Vitamin C is required for enzyme reactions that produce the neurotransmitters serotonin and norepinephrine and is essential for the synthesis of carnitine which is required for the transport of fat to the mitochondria for the production of energy. Vitamin C is involved in the metabolism of cholesterol to bile acids which may contribute to healthy blood cholesterol levels or prevent formation of gall stones. It is an essential co-factor in processes that underlie neural maturation, neuroprotection and neurotransmission. Vitamin C is effective at removing lead, arsenic and cadmium and is important in detoxifying the body.
  • Vitamin D3
    Vitamin D plays an important role in calcium and phosphorus homeostasis by regulating bone resorption, affecting absorption of calcium in the gut, and by regulating calcium losses in urine. In the kidney, vitamin D works with estrogen to regulate renal tubular reabsorption of calcium and phosphorus. In bones, vitamin D works in conjunction with parathyroid hormone to regulate the release of calcium and phosphorus from the bones into the bloodstream. Vitamin D also regulates the gene coding for synthesis of a calcium binding protein known as calbindin, which participates in calcium transport. The generic roles of vitamin D have been confirmed in over 50 genes extending beyond balancing mineral metabolism. Vitamin D has also been shown to bind to receptors the prostate, liver, thyroid, and brain. Low serum levels of vitamin D are associated with cognitive impairment in older adults1 and higher vitamin D intake has been associated with a lower risk of developing Alzheimer’s disease in older women.2 Vitamin D also has potent immune system modulating effects.3
    1. Peterson A, Mattek N, Clemons A, et al. Serum vitamin D concentrations are associated with falling and cognitive function in older adults. The journal of nutrition, health & aging. Oct 2012;16(10):898-901.
    2. Annweiler C, Rolland Y, Schott AM, et al. Higher vitamin D dietary intake is associated with lower risk of alzheimer's disease: a 7-year follow-up. The journals of gerontology. Series A, Biological sciences and medical sciences. Nov 2012;67(11):1205-1211.
    3. Prietl B, Treiber G, Pieber TR, Amrein K. Vitamin D and immune function. Nutrients. Jul 2013;5(7):2502-2521.
  • Vitamin E
    Vitamin E is a vital antioxidant. It protects polyunsaturated fatty acids from oxidation by destroying peroxyl radicals. It also improves circulation, aids tissue repair, promotes normal blood clotting, maintains healthy nerves and muscle and strengthens capillary walls. Vitamin E is also known to inhibit the activity of protein kinase C, as well as to affect the expression and activity of immune and inflammatory cells. Vitamin E may be involved in signal transduction in neuronal cells since it is associated with neuronal cell membranes and other lipids in the nervous system. Vitamin E intake in combination with vitamin B6 and B12 was associated with better performance on visuospatial recall and abstraction tests in normally aging older participants (<60 years) in a 6 year longitudinal study.1
    1. La Rue A, Koehler KM, Wayne SJ, Chiulli SJ, Haaland KY, Garry PJ. Nutritional status and cognitive functioning in a normally aging sample: a 6-y reassessment. Am J Clin Nutr. Jan 1997;65(1):20-29.
  • Vitamin K2
    Vitamin K is required for the production of prothrombin, which is essential for blood clotting. It is also critical for bone formation and repair. There are three forms of Vitamin K, which are dependent on their source. Vitamin K1 is derived from plants, Vitamin K2 is synthesized by microflora in the small and large intestine and Vitamin K3 is synthetic. Vitamin K2 has been shown in vitro and in vivo to inhibit bone resorption substances such as prostaglandin E2 and interleukin-6 and to enhance human osteoblast-induced mineralization.
  • Thiamine (Vitamin B1)
    Thiamine enhances circulation and is important in blood formation, carbohydrate metabolism and the production of hydrochloric acid, which aids in digestion. Thiamine is important in reactions that are involved in the synthesis of nucleotides, DNA, RNA, and NADPH. Thiamine has an important function in nerve membranes and in nerve conduction, although the mechanism is unclear. Thiamine also acts as an antioxidant, protecting the cells from aging. Thiamine turns glucose into energy. Thiamine supplementation has been associated with having greater energy, faster reaction times and improved mental clarity.1,2
    1. Benton D, Donohoe RT. The effects of nutrients on mood. Public health nutrition. Sep 1999;2(3A):403-409.
    2. Benton D, Griffiths R, Haller J. Thiamine supplementation mood and cognitive functioning. Psychopharmacology. Jan 1997;129(1):66-71.
  • Riboflavin (Vitamin B2)
    Riboflavin is necessary for red blood cell formation, antibody production, cellular respiration and growth. It is needed for the uptake of oxygen in body as well as the metabolism of the amino acid tryptophan, which is converted to niacin in the body.
  • Niacinamide (Vitamin B3)
    Niacin is needed for proper circulation and healthy skin. It supports the functioning of the nervous system. It aids in the metabolism of fats, carbohydrates and proteins. Niacin also lowers cholesterol and has been shown to enhance memory. Niacin taken daily has been shown to improve memory in both young and old individuals.1
    1. Morris MC, Evans DA, Bienias JL, et al. Dietary niacin and the risk of incident Alzheimer's disease and of cognitive decline. J Neurol Neurosurg Psychiatry. Aug 2004;75(8):1093-1099.
  • Pantothenic Acid (Vitamin B5)
    Pantothenic acid is important in the production of adrenal hormones, the formation of antibodies and plays a role in the conversion of fats, carbohydrates and proteins into energy.
  • Pyridoxine (Vitamin B6)
    Pyridoxine is a water-soluble vitamin essential in the metabolic pathways of amino acids, glucose, and fatty acids and is a cofactor in the production of neurotransmitters including serotonin, epinephrine, norepinephrine, and GABA. It is required by the nervous system and is needed for normal brain function as well as DNA synthesis. Supplementation with Vitamin B6 alone and in combination with other nutrients has been shown to be helpful to improve attention in children.1-4
    1. Mousain-Bosc M, Roche M, Polge A, Pradal-Prat D, Rapin J, Bali JP. Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders. Magnesium research : official organ of the International Society for the Development of Research on Magnesium. Mar 2006;19(1):46-52.
    2. Mousain-Bosc M, Roche M, Rapin J, Bali JP. Magnesium VitB6 intake reduces central nervous system hyperexcitability in children. J Am Coll Nutr. Oct 2004;23(5):545S-548S.
    3. Kidd PM. Attention deficit/hyperactivity disorder (ADHD) in children: rationale for its integrative management. Alternative medicine review : a journal of clinical therapeutic. Oct 2000;5(5):402-428.
    4. Coleman M, Steinberg G, Tippett J, et al. A preliminary study of the effect of pyridoxine administration in a subgroup of hyperkinetic children: a double-blind crossover comparison with methylphenidate. Biol Psychiatry. Oct 1979;14(5):741-751.
  • Folate
    Folic acid is essential for energy production and the formation of red and white blood cells. The biological functions of folate all stem from the roles of folate coenzymes in one-carbon metabolism. Folate coenzymes mediate transfer of one carbon units (methyl or methylene groups) in biochemical reactions. Folate coenzymes are essential for nucleic acid metabolism in the synthesis of DNA and synthesis of methionine. Methionine is required for the synthesis of S-adenosylmethionine (SAMe), a methyl group donor used in methylation reactions including methylation of DNA and RNA. Methylation of DNA is essential for normal development and may impact transcription of genes.
  • Vitamin B12
    Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. It aids folic acid in the regulation and formation of red blood cells and helps in the utilization of iron. It is required for the synthesis of protein and the metabolism of carbohydrates and fats. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine. Methionine is required for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 different substrates, including DNA, RNA, hormones, proteins, and lipids. L-methylmalonyl-CoA mutase converts L-methylmalonyl-CoA to succinyl-CoA in the degradation of propionate, an essential biochemical reaction in fat and protein metabolism. Succinyl-CoA is also required for hemoglobin synthesis.
  • Biotin
    Biotin is a member of the vitamin B complex family and is a cofactor in four carboxylase enzymes located in the brain, kidney, heart and liver. These biotin-dependent enzymes aids in cell growth, fatty acid production and in the metabolism of carbohydrates, fats and proteins. Biotin promotes healthy sweat glands, nerve tissue and bone marrow. Biotin is stored in the mitochondria, and that it acts as a coenzyme in bicarbonate-dependent carboxylation reactions.

Essential Minerals

  • Calcium
    Calcium is vital for the formation of strong bones and teeth and the maintenance of healthy gums. It is present in blood, extracellular fluid, muscle, and other tissues. It is essential for nerve transmission, muscle contraction, vascular contraction, vasodilation, glandular secretion, cell membrane and capillary permeability, enzyme reactions, respiration, renal function, and blood coagulation. It also plays a role in neurotransmitter and hormone release and storage, uptake and binding of amino acids, cyanocobalamin (vitamin B12) absorption, and gastrin secretion.
  • Magnesium
    Magnesium is a mineral essential in a variety of cellular processes including cellular respiration, protein synthesis, membrane stability, regulation of vascular tone and is important in the neuromuscular and cardiovascular systems.1 More than 300 enzyme systems use magnesium as a cofactor. As magnesium is required for stabilization of the nerve cell, chronic deficiencies can interfere with the transmission of nerve impulses, resulting in irritability and restlessness. Supplementing the body with magnesium can reduce inflammation2 and promote relaxation and calm.
    1. Swaminathan R. Magnesium metabolism and its disorders. The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists. May 2003;24(2):47-66.
    2. Nielsen FH, Johnson LK, Zeng H. Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep. Magnesium research : official organ of the International Society for the Development of Research on Magnesium. Dec 2010;23(4):158-168.
  • Iodine
    Iodine’s major function in the body is its role in the formation of thyroid hormones. Thyroid hormones stimulate basal rate of metabolism, oxygen consumption and heat production. They are necessary for normal nervous system development and linear growth. Most organ systems are directly or indirectly under the influence of thyroid hormones.
  • Zinc
    Zinc plays a role in many aspects of health, probably due to its essential role in over 200 enzyme reactions.1 The functions of zinc support normal growth and development throughout life but especially during pregnancy, childhood, and adolescence. Zinc is a structural component of many proteins, hormones, hormone receptors and neuropeptides2 and is involved in protein, DNA, and RNA synthesis, as well as in cell division. It is required for protein synthesis and collagen formation. Zinc promotes a healthy immune system and is involved in wound healing. Zinc is a constituent of insulin and the antioxidant superoxide dismutase. Zinc is an effective detoxifier, lowering levels of lead and cadmium in the body.
    1. 1. Huskisson E, Maggini S, Ruf M. The influence of micronutrients on cognitive function and performance. The Journal of international medical research. Jan-Feb 2007;35(1):1-19.
    2. Fabris N, Mocchegiani E. Zinc, human diseases and aging. Aging (Milano). Apr 1995;7(2):77-93.
  • Copper
    Copper has an essential role in the biochemistry of living organisms. It is required for normal infant development, red and white blood cell maturation, iron transport, bone strength, cholesterol metabolism, myocardial contractility, glucose metabolism, brain development, immune function and protection against oxidative stress.
  • Selenium
    Most selenium-containing proteins (selenoprotein) have enzymatic functions. Selenium is best known for its role in the glutathione peroxidase enzyme system, one of the most vital antioxidant defense systems in the body. Selenium’s effects are enhanced in the presence of vitamin E. Selenium antagonizes the effects of toxic metals such as cadmium, arsenic and mercury. The selenoprotein iodothyronine deiodinase is required for synthesis of thyroid hormone.
  • Manganese
    Manganese is required for bone growth and is involved in the formation of cartilage and synovial fluid of the joints. It is essential in protein, fat, and carbohydrate metabolism. Manganese functions, like other trace elements, as an enzyme activator and as a constituent of metalloenzymes. Manganese is the preferred metal cofactor for glycosyltransferases. These are important in the synthesis of glycoproteins which help in synthesis of myelin and clotting factors.
  • Chromium
    Chromium is involved in the metabolism of glucose and facilitates glucose transport from blood into the cells of various tissues. It is vital in the synthesis of cholesterol, fats and proteins. This mineral maintains stable blood sugar levels through proper insulin utilization. Chromium may stabilize nucleic acids (mainly RNA) against structural distortions and may stimulate synthesis of fatty acids and cholesterol in the liver. Chromium chelated with picolinate enables chromium to enter the body’s cells more readily, allowing insulin to function more effectively.
  • Molybdenum
    Molybdenum functions mainly as an enzyme cofactor. It is an essential mineral required in small amounts for nitrogen metabolism. It is also important in bone growth and maintaining strong teeth. It promotes normal cell function, aids in the activation of enzymes and is a component of the metabolic enzyme xanthine oxidase.

Other Nutrients

  • Choline
    Choline is needed for the proper transmission of nerve impulses in addition to gallbladder regulation, liver function and lecithin formation. Choline is important in maintaining the structural integrity of cell membranes and for cholinergic neurotransmission. It also functions as a methyl donor for the synthesis of many endogenous compounds. Choline has been shown to be helpful in improving cognitive performance in a young, cognitively healthy, community-based population of 1,391 subjects.1
    1. Poly C, Massaro JM, Seshadri S, et al. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr. Dec 2011;94(6):1584-1591.
  • Lutein
    Lutein is a xanthophyll carotenoid found concentrated in the macula of the eye, where vision occurs. In antioxidant that inhibits lipid peroxidation and keeps eyes safe from oxidative stress, which helps in the protection of ocular function and prevention of cardiovascular disease.
  • Zeaxanthin
    Zeaxanthin is a xanthophyll carotenoid that is contained within the retina of the eye and helps in the protection of ocular function.
  • Resveratrol
    Resveratrol is a member of a group of plant compounds called polyphenols. Resveratrol has been shown to have antioxidant properties, protecting the body against the type of damage linked to cancer and heart disease. Resveratrol is found in the skin of red grapes, but other sources include peanuts and berries. Resveratrol may protect nerve cells from damage and the buildup of plaque that can lead to Alzheimer's.1 Resveratrol helps to prevent insulin resistance, a condition in which the body becomes less sensitive to the effects of the blood sugar-lowering hormone, insulin.2
    1. Joseph JA, Fisher DR, Cheng V, Rimando AM, Shukitt-Hale B. Cellular and behavioral effects of stilbene resveratrol analogues: implications for reducing the deleterious effects of aging. Journal of agricultural and food chemistry. Nov 26 2008;56(22):10544-10551.
    2. Szkudelski T, Szkudelska K. Anti-diabetic effects of resveratrol. Ann N Y Acad Sci. Jan 2011;1215:34-39.
  • Hesperidin flavonoid complex
    Hesperidin is a plant chemical that is classified as a bioflavonoid. The human body cannot produce bioflavonoids, they must be supplied in the diet. Bioflavonoids act synergistically with Vitamin C to protect and preserve the capillaries. They also have an antibacterial effect and promote circulation.
  • Boron
    Boron is a mineral needed in trace amounts for healthy bones and muscle growth. It also aids in the metabolism of calcium, phosphorous and magnesium. It enhances brain function, promotes alertness and aids the body in utilizing energy from fats and sugars.
  • Silicon
    Silicon is needed for the formation of collagen for bones and connective tissue. It helps produce healthy skin, hair and nails. It is also needed to maintain the flexibility in arteries, helping to prevent cardiovascular disease.
  • Fruit and Vegetable Blend
    This blend was added to provide fruit and plant-based sources of phytochemicals to promote health, improve brain vitality and enhance immune function. Alfalfa sprouts and broccoli contain superoxide dismutase, an important metabolic enzyme with potent antioxidant properties. Carrots, broccoli, tomatoes, wild blueberries, strawberries and acai contain a variety of carotenoids, flavonoids and anthocyanidins, which are efficient free-radical scavengers. Evidence in the scientific literature shows that consistent, long-term, consumption of fruits and vegetables is associated with delayed cognitive decline,1-3 so this unique blend was included in Neurovite Plus to provide this essential nutrient support.
    1. Devore EE, Kang JH, Breteler MM, Grodstein F. Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol. Jul 2012;72(1):135-143.
    2. Kang JH, Ascherio A, Grodstein F. Fruit and vegetable consumption and cognitive decline in aging women. Ann Neurol. May 2005;57(5):713-720.
    3. Loef M, Walach H. Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. The journal of nutrition, health & aging. Jul 2012;16(7):626-630.
  • Proprietary Brain Boosting Blend
    This combination of brain directed nutrients including acetyl-l-carnitine, alpha-lipoic acid, Phosphatidyl serine and Coenzyme Q10 were included to help support mitochondrial function, antioxidant levels, healthy blood sugar regulation, proper cell membrane maintenance and assist in the generation of cellular energy.
  • Phosphatidylserine
    Phosphatidylserine (PS) is a fat-soluble phospholipid that is an essential component of cell membranes. It is the most abundant phospholipid in the brain and is important in neuronal membrane function including maintaining the cellular environment, signal transduction, vesicle release, cell-cell communication and cell growth regulation. PS is located in the inner layer of cellular membranes and has a variety of structural and functional roles including cell membrane fluidity, modulation of cellular receptors and production and packaging of neurotransmitters including norepinephrine, acetylcholine, dopamine and serotonin. Several placebo-controlled clinical research trials demonstrate that PS is effective at improving learning, memory and concentration.1-5
    1. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern. Med Rev. 1996;1:70-84.
    2. Cenacchi T, Bertoldin T, Farina C, Fiori MG, Crepaldi G. Cognitive decline in the elderly: a double-blind, placebo-controlled multicenter study on efficacy of phosphatidylserine administration. Aging (Milano). Apr 1993;5(2):123-133.
    3. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacology bulletin. 1992;28(1):61-66.
    4. Klinkhammer P, Szelies B, Heiss W-D. Effect of phosphatidylserine on cerebral glucose metabolism in Alzheimer's disease. Dementia. 1990;1:197-201.
    5. Amaducci L. Phosphatidylserine in the treatment of Alzheimer's disease: results of a multicenter study. Psychopharmacology bulletin. 1988;24(1):130-134.
  • Acetyl-L-Carnitine (ALC)
    ALC is a natural compound essential for normal mitochondrial function. It facilitates the transport of long-chain fatty acids across the mitochondrial membrane, promoting enhanced cellular energy production. This dietary antioxidant functions to improve free radical scavenging as well as inhibition of pro-inflammatory pathways which maintains and repairs neuronal damage.1 It is also thought to influence the cholinergic system by promoting the synthesis and release of acetylcholine. Clinical trials demonstrate the ability of ALC as monotherapy2-4 or in combination with targeted nutrients5,6 to support cognition and mood in healthy patients7 as well as those with cognitive decline.3,4,7
    1. McDaniel MA, Maier SF, Einstein GO. "Brain-specific" nutrients: a memory cure? Nutrition. Nov-Dec 2003;19(11-12):957-975.
    2. Montgomery SA, Thal LJ, Amrein R. Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. Int Clin Psychopharmacol. Mar 2003;18(2):61-71.
    3. Thal LJ, Carta A, Clarke WR, et al. A 1-year multicenter placebo-controlled study of acetyl-L-carnitine in patients with Alzheimer's disease. Neurology. Sep 1996;47(3):705-711.
    4. Salvioli G, Neri M. L-acetylcarnitine treatment of mental decline in the elderly. Drugs under experimental and clinical research. 1994;20(4):169-176.
    5. Remington R, Bechtel C, Larsen D, et al. A Phase II Randomized Clinical Trial of a Nutritional Formulation for Cognition and Mood in Alzheimer's Disease. J Alzheimers Dis. 2015;45(2):395-405.
    6. Chan A, Remington R, Kotyla E, Lepore A, Zemianek J, Shea TB. A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia. The journal of nutrition, health & aging. Mar 2010;14(3):224-230.
    7. Brooks JO, 3rd, Yesavage JA, Carta A, Bravi D. Acetyl L-carnitine slows decline in younger patients with Alzheimer's disease: a reanalysis of a double-blind, placebo-controlled study using the trilinear approach. Int Psychogeriatr. Jun 1998;10(2):193-203.
  • Alpha-Lipoic Acid
    Alpha lipoic acid is a compound found in the mitochondria of cells that is important in energy production. Supplemental ALA has a powerful antioxidant capacity1,2 and has been found to increase the cellular uptake of glucose,3 making it an important regulator of blood sugar levels. ALA is both water and fat soluble and can regenerate endogenous antioxidants, such as vitamin E, vitamin C, and glutathione, chelation of metal ions and repair of oxidatively damaged proteins.1,4,5 Preliminary evidence suggests that the neuroprotective properties of alpha-lipoic acid slowed cognitive decline in those with age related cognitive decline.6,7
    1. Bast A, Haenen GR. Lipoic acid: a multifunctional antioxidant. Biofactors. 2003;17(1-4):207-213.
    2. Kishi Y, Schmelzer JD, Yao JK, et al. Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy. Diabetes. Oct 1999;48(10):2045-2051.
    3. Biewenga GP, Haenen GR, Bast A. The pharmacology of the antioxidant lipoic acid. General pharmacology. Sep 1997;29(3):315-331.
    4. Packer L. Antioxidant properties of lipoic acid and its therapeutic effects in prevention of diabetes complications and cataracts. Ann N Y Acad Sci. Nov 17 1994;738:257-264.
    5. Shinto L, Quinn J, Montine T, et al. A randomized placebo-controlled pilot trial of omega-3 fatty acids and alpha lipoic acid in Alzheimer's disease. J Alzheimers Dis. 2014;38(1):111-120.
    6. Maczurek A, Hager K, Kenklies M, et al. Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Advanced drug delivery reviews. Oct-Nov 2008;60(13-14):1463-1470.
    7. Sauer J, Tabet N, Howard R. Alpha lipoic acid for dementia. Cochrane Database Syst Rev. 2004(1):CD004244.
  • Coenzyme Q10
    CoQ10 is a key component of the mitochondrial electron chain, acting as an electron carrier in the lipid phase of the mitochondrial membrane, producing energy. CoQ10 is essential for ATP production. It is present in cell membranes at high concentrations, acting as an antioxidant scavenger of free radicals and taking part in regeneration of other key antioxidants such as tocopherol (vitamin E) and ascorbate (vitamin C). CoQ10 may prevent initiation and propagation of lipid peroxidation in plasma lipoprotein biological membranes. Thus, CoQ10 prevents LDL oxidation, indicating a potential role reducing risk of cardiovascular disease.
  • Digestive Enzyme Blend
    Enzymes are essential to many body functions. Digestive enzymes are secreted along the gastrointestinal tract and aid in breaking down food, so the nutrients are easily absorbed into the bloodstream. We have included lipase, amylase, lactase and cellulose to assist the digestive process.

Frequently Asked Questions

How do I take NeuroVite Plus?
Adults and teens should take 4 capsules daily, or as directed by a nutritionally informed physician. This product is best taken with meals in divided doses, such as 2 capsules with each of your two earliest meals of the day.
Is there Vitamin D in this multivitamin supplement?
Yes, there are 2000 IU in the recommended serving. This is considerably more than most multiples provide.
Can children take NeuroVite Plus?
NeuroVite Plus was formulated for the adult body, though it is safe for kids to take. For kids we prefer to recommend our brain-directed, multi-nutrient multivitamin supplement called Kids’ NeuroVite. It comes in delicious orange flavored chewables that kids love!
What’s the difference between NeuroVite Plus and other multivitamins?
Our NeuroVite Plus is a highest-quality, top of the line, multifunctional dietary supplement that surpasses conventional brands in its range and potency of brain-targeted nutrients. It is more potent for eye health than many eye products, supplies more antioxidant potency than many antioxidant supplements. Its diverse set of over 50 nutrients makes NeuroVite Plus the dietary supplement of choice for anyone seeking optimal physical and mental fitness.

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