Promotes healthy mood, enhances SAMe's mood benefits, supports healthy methyl and homocysteine metabolism, important cell water regulator
Markedly Enhances the Mood Benefits of SAMe (S-AdenosylMethionine)
Betaine (trimethylglycine, TMG) occurs naturally in our cells. Taking betaine can improve SAMe's mood benefits: in a clinical trial, subjects who received SAMe (750 mg/day) plus betaine (375 mg/day) performed better than SAMe alone (800 mg/day) on measures of worry, helplessness and worthlessness, agitation, and physical efficiency.
Potent Source of Methyl Groups for Numerous Life Processes
SAMe provides methyl groups for DNA production and repair and for epigenetic gene regulation; for brain production of the hormone melatonin and the neurotransmitters dopamine, epinephrine, and norepinephrine; to insulate nerve cells for high signaling efficiency; even to make phospholipids that underpin cell structure. Betaine is a highly effective methyl donator that helps the body make and conserve SAMe.
Supports Healthy Homocysteine Metabolism
Making SAMe generates homocysteine, which can have toxic effects. Betaine readily provides methyl needed to recycle homocysteine. Betaine bypasses enzyme systems that get methyl from folate and vitamin B12 but are vulnerable to inherited gene errors. Many individuals who are unable to achieve healthy homocysteine regulation by taking folate and vitamin B12 experience success by taking betaine.
Important Molecular Tool for Regulating Cell Water Content
Regulation of water content is a survival issue for all human cells. With too little water they shrink and their enzymes can't work; with too much, they swell and can rupture. They use betaine to sensitively regulate their water content.
Ingredients & Facts
Betaine or trimethylglycine (TMG) is integral to human metabolism and clinically proven to help the brain, liver, and other organs. This small molecule is loaded with methyl groups, and is an effective metabolic backup for SAMe (s-adenosylmethionine), which is an essential cofactor for some 200 enzymes. By helping the body conserve SAMe, betaine also helps conserve the body's antioxidant defenses, which overlap with SAMe metabolism. Betaine also is a potent means for controlling potentially toxic homocysteine. The normal (and unavoidable) metabolism of SAMe generates homocysteine, and betaine may be the most efficient means for recycling it (to methionine, which then can be used to make SAMe again). We get betaine from beets (hence its name), spinach, and a few other foods, but some individuals have low blood betaine and correspondingly show metabolic difficulties. Supplementing with Betaine TMG from BrainMD Health helps ensure that the brain and body will receive sufficient methyl to fulfill their many duties. By facilitating healthy cell water regulation, methylation and antioxidant defense this product supports fundamental human life processes.